Benzodiazepines


Benzodiazepines
Equivalent to 1 mg lorazepam 
in mg
Peak plasma Cmax 
in hrs
1/2 life (metabolites 1/2 life) 
in hrs
Lorazepam (Ativan) 1 1-6 8-24
Clonazepam (Rivotril) 0,25 1-4 19-60
Diazepam (Valium) 5 1-2 14-80 (30-200)
Oxazepam (Serax) 15 1-4 3-35
Alprazolam (Xanax) 0,5 1-2 6-27
Temazepam (Restoril) 10 2,5 3-25
Bromazepam (Lectopam) 3 0,5-4 8-30
Chlordiazepoxide (Librium) 25 1-4 4-29 (28-100)
Flurazepam (Dalmane) 15 0,5-1 0,3-3 (40-250)
Nitrazepam (Mogadon) 2,5 0,5-7 15-48
Triazolam (Halcion) 0,25 1-2 1,5-5

(Clinical Handbook of Psychotropic Drugs 17th Edition, Bezchlibnyk-Butler, pp154-158, 2007)

(A Way of Conceptualizing Benzodiazepines to Guide Clinical Use, Preskorn S, Journal of Psychiatric Practice, v21 n6 (201511): 436-441)
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